extended panel genotyping plate layout


extended panel genotyping plate layout

The Extended Panel of QTRACE® INDEL Assays

For the vast majority of patients, there is a choice between multiple informative assays available for the monitoring of chimerism. However, in rare cases including patients receiving a second transplant or highly similar siblings, there may be need for additional markers allowing to distinguish between donor and recipient DNA.

In order to satisfy these needs, JETA Molecular has introduced the Extended Panel of QTRACE® INDEL Assays in March 2020. Thirty-four loci, which are unique to JETA, have been added with the Extended Panel. These Assays are also available in dPCR-validated configurations.

 

80 Assays for qPCR and dPCR Chimerism Monitoring

The Extended Panel of QTRACE® and DigitalTRACE™ INDEL Assays comprises a pre-arrayed genotyping plate and a set of 34 additional INDEL markers designed to broaden the Standard Panel of 46 QTRACE® and DigitalTRACE™ Assays for chimerism testing.

Together with the Standard QTRACE® and DigitalTRACE™ Assay Panels, our customers may now take advantage of the use of the total number of 80 unique INDEL Assays available for chimerism testing. This makes QTRACE® and DigitalTRACE™ INDEL Assays the widest set of chimerism monitoring markers currently available on the market.

This System is the only commercial qPCR/dPCR test which offers resolution on the order of Short Tandem Repeat Analysis. With 80 bi-allelic loci tested, theoretically every person on the planet will have a unique genotype with our system.


 

QTRACE® INDEL ASSAY TARGETS: THE STANDARD PANEL (BLUE) AND THE EXTENDED PANEL (ORANGE)

 

MONITORING

Measure Fractional Abundance of Donors/Recipients
High Sensitivity Provides Earlier Detection Than STR
Unambiguous Data, Rapid Analysis

REAGENTS

Pre-Arrayed Extended Panel Typing Plates
34 Additional INDEL Monitoring Assays
Ultimate Probability of Finding an Informative Assay

SOFTWARE

Automated Protocols
Multi-Instrument Capability
Longitudinal Sample Tracking